PRGF® - Endoret Facial Rejuvenation

PRGF®-Endoret® Technology Applications

Completely natural facial rejuvenation that only you can give yourself. PRGF (Plasma Rich in Growth Factors) Facial Rejuvenation Treatment.

PRGF-Endoret facial rejuvenation treatments are one of the world’s best-documented procedures, with over 20 years of clinical data and supported by more than 70 scientific papers.

It works by extracting the growth factors and stem cells from your own plasma which we use in an all-natural mesotherapy treatment to push back the hand of time on your skin aging clock.

PRGF is applied to the face, neck and hands skin using a fine needle in a short pain-free session. The injected plasma contains proteins which have a biological activity, and this stimulates tissue regeneration, increase in the skin’s thickness, smoothness, and luminosity, turning back the effects of the aging process.

Benefits of PRGF

  • Increased skin consistency

  • Wrinkle reduction

  • Brighter complexion

  • There are no changes in facial expressions

  • Increased skin hydration and skin cooling feeling

  • Slows down the aging process

  • Rejuvenation and renewal of the skin

  • Collagen production is increased


Sking Aging


1. Epidermis

There are variations in the size, shape and properties of this layer, with a decrease of melanocytes and Langerhans cells as well as a flattening of the epidermis.

2. Dermis

There is a reduction of the thickness of this layer, vascularity, degeneration of the collagen and elastin fibers and a decrease of hyaluronic acid production.

3. HYpodermis

There is a decrease in cell number and atrophy of the sweat glands.

Sking Aging

Treatment With Prgf ®-Endoret ®

1. Epidermis

Mesotherapy and plasma rich in growth factors treatment getsthe regeneration of this layer by increasing the number of cells inside it.

2. Dermis

El PRGF®-Endoret® causes the secretion of endogenous hyaluronic acid; increases production of elastin and pro-collagen, and anangiogenic effect that increases the number of vessels in this area.

3. HYpodermis

With this treatment, the fat cells get divided quicker, increasing their overall number.


Facial Antiaging

PRGF®-Endoret® in aesthetic application has the ability to restore the vitality of the skin by increasing hydration, promoting angiogenesis (formation of blood vessels), bringing a greater supply of nutrients to our skin. Also no contraindications or allergies are present being a product coming from the patient himself.

"LIFTING" effect

From all the choices in the market, treatments stimulating skin regeneration using growth factors extracted from patient's own plasma, should be highlighted. They are involved in the intercellular communication triggering a series of key biological effects in the tissue repair and regeneration such as directed cell migration (chemotaxis), proliferation and cells differentiation and extracellular matrix synthesis.

Post-Infiltration Results
  • Increased consistency

  • Reduction of wrinkles

  • Increased brightness

  • No change in facial expression.

  • Biostimulation of the treated areas.

  • Compatible with other antiaging treatments.

  • Increased facial hydration and cooling sensation

Age For Treatments

This treatment is recommended on a Preventative level to slow the aging process or from 45 with regenerative and corrective purposes.

Number Of Sessions

It is recommended to do three sessions in the first three months. Subsequently, the process is personalized, with between 1 to 3 annual session. Follow ups will depend on age and skin types.

PRGF®-ENDORET® Benefits: In Aesthetics

PRGF®-ENDORET® • Botulinum Toxin • Hyaluronic Acid

(*) One single kit allows all above areas complete treatment.

Skin Hydration Study

Skin hydration gets increased with PRGF®-Endoret® use both 3 and 6 months after treatment.

Percentage of evolution of the corneometry level, comparing with the basal level in both treatment groups. * Number of patients: 100.

Patients Satisfaction Level Study

Higher amount of patients accepted the PRGF®-Endoret® treatment versus hyaluronic acid one.

Further Reading

The Beauty Worlds Newest Secret. PRGF is the Natural way and answer!